Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231739 | 0.90 | PPARA (0.55) | PTPN1ALDH1A1NPSR1PPARACA2 | |
| SCHEMBL8981831 | 0.88 | LMNA (0.52) | PTPN1ALDH1A1NPSR1PPARALMNA | |
| SCHEMBL8981839 | 0.88 | LMNA (0.52) | PTPN1ALDH1A1NPSR1PPARALMNA | |
| SCHEMBL8981845 | 0.88 | LMNA (0.52) | PTPN1ALDH1A1NPSR1PPARALMNA | |
| SCHEMBL13524845 | 0.84 | PTPN1 (0.55) | PTPN1ALDH1A1NPSR1PPARACA2 | |
| SCHEMBL13847876 | 0.83 | PTPN1 (0.54) | PTPN1ALDH1A1NPSR1PPARACA2 | |
| SCHEMBL8981902 | 0.82 | DNMT3A (0.64) | DNMT3AHDAC1HDAC6 | |
| SCHEMBL8981741 | 0.81 | LMNA (0.49) | PTPN1ALDH1A1NPSR1CA2LMNA | |
| SCHEMBL8981731 | 0.81 | LMNA (0.49) | PTPN1ALDH1A1NPSR1CA2LMNA | |
| SCHEMBL8981737 | 0.81 | LMNA (0.49) | PTPN1ALDH1A1NPSR1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207158-B1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2005-05-25 | — | — | EP | claimed |
| US-6780431-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONISTS; METABOLIC DISEASES SUCH AS DIABETES AND HYPERLIPIDEMIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-08-24 | — | — | US | claimed |
| EP-1207158-A1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | claimed |