Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | GFER | P55789 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232538 | 0.98 | BCHE (0.59) | BCHEACHERAB9ANPC1GFER | |
| SCHEMBL6239333 | 0.85 | TP53 (0.64) | BCHEACHERAB9ANPC1GFER | |
| SCHEMBL6236251 | 0.85 | NPC1 (0.58) | BCHEACHERAB9ANPC1GFER | |
| SCHEMBL27938349 | 0.80 | HTR2B (0.49) | BCHEACHETP53HTR3AALDH1A1 | |
| SCHEMBL4486269 | 0.79 | BCHE (0.59) | BCHEACHERAB9ANPC1GFER | |
| SCHEMBL4483813 | 0.79 | BCHE (0.59) | BCHEACHERAB9ANPC1GFER | |
| SCHEMBL31154250 | 0.79 | TP53 (0.44) | BCHEACHERAB9ANPC1GFER | |
| SCHEMBL1666284 | 0.78 | MAPT (0.50) | TP53HPGDNPSR1POLBTRPC3 | |
| SCHEMBL31154214 | 0.78 | BCHE (0.39) | BCHEACHERAB9ANPC1GFER | |
| SCHEMBL2241920 | 0.77 | BCHE (1.00) | BCHEACHERAB9ANPC1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |