Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K8 | P41279 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | GALR1 | P47211 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GALR2 | O43603 | 3/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031340 | 0.91 | GALR1 (0.47) | MAP3K8DRD2VNN1GALR1KDM4E | |
| SCHEMBL4838450 | 0.90 | GALR1 (0.39) | MAP3K8DRD2VNN1GALR1KDM4E | |
| SCHEMBL5551996 | 0.89 | GALR1 (0.47) | DRD2GALR1GALR2LMNA | |
| SCHEMBL7190657 | 0.87 | MAP3K8 (0.39) | MAP3K8DRD2VNN1GALR1KDM4E | |
| SCHEMBL6239105 | 0.84 | HTT (0.44) | MAP3K8VNN1KDM4EALDH1A1POLB | |
| SCHEMBL4832495 | 0.84 | DRD2 (0.50) | DRD2GALR1GALR2 | |
| SCHEMBL4829744 | 0.84 | DRD2 (0.50) | DRD2GALR1GALR2 | |
| SCHEMBL5553540 | 0.83 | GALR1 (0.46) | MAP3K8DRD2VNN1GALR1KDM4E | |
| SCHEMBL4836437 | 0.82 | GALR1 (0.48) | DRD2GALR1GALR2 | |
| SCHEMBL14294122 | 0.81 | GALR1 (0.49) | MAP3K8DRD2VNN1GALR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |