Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYBB | P04839 | 2/20 | 0.38 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.38 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032201 | 0.90 | GALR1 (0.44) | MAP3K8MAPTMAPK1TDP1IL1B | |
| SCHEMBL5029055 | 0.88 | RAB9A (0.42) | MAP3K8MAPTMAPK1TDP1IL1B | |
| SCHEMBL5551996 | 0.88 | GALR1 (0.47) | MAPTTSHR | |
| SCHEMBL6231894 | 0.84 | MAP3K8 (0.40) | MAP3K8VNN1KDM4EALDH1A1HPGD | |
| SCHEMBL14294395 | 0.84 | VNN1 (0.46) | MAP3K8IL1BVNN1KDM4EALDH1A1 | |
| SCHEMBL4835588 | 0.83 | GALR1 (0.43) | MAP3K8VNN1KDM4EALDH1A1HPGD | |
| SCHEMBL7190657 | 0.83 | MAP3K8 (0.39) | MAP3K8MAPTVNN1KDM4EALDH1A1 | |
| SCHEMBL4832495 | 0.82 | DRD2 (0.50) | — | |
| SCHEMBL4829744 | 0.82 | DRD2 (0.50) | — | |
| SCHEMBL6233857 | 0.82 | PIK3CA (0.41) | MAP3K8VNN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |