Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | MPC2 | O95563 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846812 | 0.85 | MAOA (0.54) | PTPN1CA2ALDH1A1NPSR1MAOA | |
| SCHEMBL8182679 | 0.83 | PTPN1 (0.79) | PTPN1CA2ALDH1A1NPSR1MAOA | |
| SCHEMBL9833547 | 0.83 | MAPT (0.52) | PTPN1ALDH1A1NPSR1SMN1; SMN2MAOA | |
| SCHEMBL14262660 | 0.81 | PTPN1 (0.68) | PTPN1CA2ALDH1A1NPSR1MAOA | |
| SCHEMBL6233368 | 0.80 | PTPN1 (0.67) | PTPN1CA2ALDH1A1NPSR1MAOA | |
| SCHEMBL13846691 | 0.80 | PTPN1 (0.67) | PTPN1CA2ALDH1A1NPSR1MAOA | |
| SCHEMBL1386331 | 0.79 | ALDH1A1 (0.56) | PTPN1CA2ALDH1A1NPSR1MAPT | |
| SCHEMBL14262536 | 0.79 | PTPN1 (0.68) | PTPN1CA2ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5707014 | 0.78 | PTPN1 (0.64) | PTPN1CA2ALDH1A1NPSR1MAOA | |
| SCHEMBL5500101 | 0.78 | PTPN1 (0.50) | PTPN1CA2ALDH1A1NPSR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213287-B1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2005-05-25 | — | — | EP | disclosed |
| US-6730687-B1 | THERAPY OF METABOLIC DISEASES SUCH AS DIABETES AND HYPERLIPIDEMIA AS AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| EP-1213287-A1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |