Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252072 | 0.92 | PTPN1 (0.39) | HCRTR1HCRTR2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL1634394 | 0.88 | PPARG (0.40) | HCRTR1HCRTR2SMN1; SMN2TSHRKDM4E | |
| SCHEMBL6216367 | 0.88 | PTPN1 (0.33) | SMN1; SMN2LMNASCN9AMAPTPPARA | |
| SCHEMBL6034666 | 0.88 | PPARG (0.36) | SMN1; SMN2KDM4ELMNASCN9AMAPT | |
| SCHEMBL6035861 | 0.87 | NPC1 (0.39) | HCRTR1HCRTR2SMN1; SMN2TSHRKDM4E | |
| SCHEMBL6036352 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4ELMNAHPGDPPARD | |
| SCHEMBL6217493 | 0.82 | SLC6A9 (0.35) | SMN1; SMN2LMNASCN9AMAPTPTPN1 | |
| SCHEMBL6221713 | 0.82 | KDM4E (0.31) | SMN1; SMN2KDM4EMAPK1MAPTPPARA | |
| SCHEMBL6035452 | 0.82 | GCGR (0.35) | HCRTR1HCRTR2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL6036437 | 0.81 | PPARG (0.41) | HCRTR1HCRTR2SMN1; SMN2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |