Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232097 | 0.92 | HCRTR1 (0.38) | PTPN1SMN1; SMN2HPGDKDM4ELMNA | |
| SCHEMBL6035857 | 0.88 | PTPN1 (0.41) | PTPN1PPARGPPARA | |
| SCHEMBL6215845 | 0.88 | PTPN1 (0.41) | PTPN1SMN1; SMN2LMNAMAPTPPARG | |
| SCHEMBL6035913 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDKDM4ELMNAMAPT | |
| SCHEMBL1634394 | 0.82 | PPARG (0.40) | SMN1; SMN2HPGDKDM4ELMNAHTT | |
| SCHEMBL6036352 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDKDM4ELMNATHRB | |
| SCHEMBL6035452 | 0.82 | GCGR (0.35) | SMN1; SMN2HPGDKDM4ELMNAMAPT | |
| SCHEMBL6036248 | 0.81 | PPARD (0.40) | SMN1; SMN2HPGDKDM4ELMNAPPARG | |
| SCHEMBL6232363 | 0.81 | PPARG (0.33) | PTPN1PPARGPPARA | |
| SCHEMBL6218384 | 0.81 | PPARG (0.33) | PTPN1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |