SCHEMBL6232116

SCHEMBL6232116

COC(=O)C1CCN1C[C@@]1(C)C=CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
LTA4H P09960 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6234411 1.00 POLB (0.33) POLBLTA4H
SCHEMBL7068078 1.00 POLB (0.33) POLBLTA4H
SCHEMBL7062108 0.87 KDM4E (0.37) POLB
SCHEMBL7064456 0.85 KDM1A (0.36)
SCHEMBL7060879 0.81 CHRM2 (0.35)
SCHEMBL7066524 0.79 FKBP1A (0.42)
SCHEMBL7064429 0.79 GRIN2B (0.36)
SCHEMBL7062940 0.78 ALDH1A1 (0.40)
SCHEMBL28094619 0.76 SMN1; SMN2 (0.43)
SCHEMBL2773153 0.68 FKBP1A (0.42) POLBLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1201653-B1 Method for racemization of optically active azetidine-2-Carboxylate SUMITOMO CHEMICAL CO (JP) 2005-04-20 EP disclosed
EP-0957089-B1 Method for racemization of optically active azetidine-2-carboxylate SUMITOMO CHEMICAL CO (JP) 2003-09-17 EP disclosed
EP-1201653-A1 Method for racemization of optically active azetidine-2-Carboxylate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 EP disclosed
US-6166224-A Method for racemization of optically active azetidine-2-carboxylate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-12-26 US disclosed
EP-0957089-A1 Method for racemization of optically active azetidine-2-carboxylate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-17 EP disclosed