Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 6/20 | 0.60 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TEC | P42680 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232769 | 0.82 | SCN4A (0.49) | SCN4ASCN9AMEN1KMT2A | |
| SCHEMBL1384902 | 0.76 | SCN4A (1.00) | SCN4ASCN9A | |
| SCHEMBL1384820 | 0.74 | SCN4A (1.00) | SCN4ASCN9ARAB9APARP10BTK | |
| SCHEMBL13168526 | 0.73 | SCN4A (0.82) | SCN4ASCN9A | |
| SCHEMBL13168542 | 0.73 | SCN4A (0.82) | SCN4ASCN9A | |
| SCHEMBL3367406 | 0.71 | SCN4A (0.79) | SCN4ASCN9AMAPTKMT2APARP15 | |
| SCHEMBL13168622 | 0.71 | SCN4A (1.00) | SCN4ASCN9AEGFRBTK | |
| SCHEMBL1386035 | 0.71 | SCN4A (1.00) | SCN4ASCN9AEGFRBTK | |
| SCHEMBL27795462 | 0.71 | SCN4A (0.74) | SCN4ASCN9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL189702 | 0.70 | RAB9A (0.53) | MAPTSMN1; SMN2KDM4ERAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |