Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 3/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 6/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232188 | 0.82 | SCN4A (0.60) | SCN4ASCN9AMEN1KMT2A | |
| SCHEMBL6255230 | 0.74 | PIK3CG (0.53) | PIK3CGUSP2ALOX15PDE4APDE4B | |
| SCHEMBL4491543 | 0.73 | FYN (0.49) | SCN4AFYNPIK3CAATRUSP2 | |
| SCHEMBL15086777 | 0.73 | FYN (0.51) | SCN4AFYNPIK3CAATRKMT2A | |
| SCHEMBL12848987 | 0.72 | RAB9A (0.68) | PIK3CGPKMALOX15MEN1KMT2A | |
| SCHEMBL6239905 | 0.70 | KMT2A (0.52) | PIK3CGMEN1KMT2A | |
| SCHEMBL14611120 | 0.70 | TSHR (0.61) | MEN1KMT2A | |
| SCHEMBL8807187 | 0.70 | GAA (0.55) | PIK3CGATMMEN1KMT2A | |
| SCHEMBL3603255 | 0.69 | PSEN1 (0.41) | PIK3CGFYNPDE4APDE4BPDE4C | |
| SCHEMBL4183271 | 0.69 | CFTR (0.47) | PIK3CGFYNPIK3CAATRPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |