Arachidin-2

Arachidin-2

SCHEMBL6232566

CC(C)=CCc1c(O)cc(C=Cc2ccc(O)cc2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 1.00
MAOB P27338 2/20 1.00
CYP19A1 P11511 5/20 0.77
PTGS2 P35354 4/20 0.77
ALOX5 P09917 4/20 0.77
PPARG P37231 8/20 0.76
PPARA Q07869 8/20 0.76
PTGS1 P23219 1/20 0.55
PTPN1 P18031 1/20 0.53
DHODH Q02127 1/20 0.53
OSBP P22059 1/20 0.53
APP P05067 1/20 0.53
PDPK1 O15530 1/20 0.53
TTR P02766 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arachidin-2 SCHEMBL31544968 1.00 MAOA (1.00) MAOAMAOBCYP19A1PTGS2ALOX5
Arachidin-2 SCHEMBL4742876 1.00 MAOA (1.00) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL13970532 0.87 CYP19A1 (1.00) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL24074948 0.87 PPARG (1.00) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL16200005 0.87 MAOB (0.76) MAOAMAOBCYP19A1PTGS2ALOX5
Chiricanine A SCHEMBL19717932 0.87 MAOA (0.77) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL24074947 0.87 MAOA (0.77) MAOAMAOBCYP19A1PTGS2ALOX5
Schweinfurthin J SCHEMBL31544937 0.86 PPARG (0.97) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL25223796 0.84 MAOA (0.73) MAOAMAOBCYP19A1PTGS2ALOX5
SCHEMBL28185918 0.84 MAOA (0.73) MAOAMAOBCYP19A1PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021072473-A1 ANTIMICROBIALS AS FEED PRESERVATIVES IRP Health Pty Ltd (AU) 2021-04-22 WO claimed
EP-1311257-B1 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INC (US) 2005-04-27 EP claimed
EP-1311257-A2 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS Insmed Incorporated (US) 2003-05-21 EP claimed
US-6552085-B2 For lowering blood glucose in a mammal INSMED INCORPORATED 2003-04-22 US claimed
US-6410596-B1 FOR LOWERING BLOOD GLUCOSE IN A MAMMAL INSMED INCORPORATED 2002-06-25 US claimed
US-20020058707-A1 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED 2002-05-16 US claimed
US-20020058701-A1 Compositions containing hypoglycemically active stilbenoids SHAMAN PHARMACEUTICALS 2002-05-16 US claimed
WO-2002013811-A2 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO claimed
WO-2002014252-A2 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO claimed
WO-2024249297-A2 POLYMERIC COMPOSITIONS WITH PRENYLATED STILBENES Cambium Biomaterials, Inc. (US) 2024-12-05 WO disclosed
WO-2021072473-A1 ANTIMICROBIALS AS FEED PRESERVATIVES IRP Health Pty Ltd (AU) 2021-04-22 WO disclosed
US-20130209617-A1 COMPOSITIONS AND METHODS FOR USE IN PROMOTING PRODUCE HEALTH PACE INTERNATIONAL, LLC (US) 2013-08-15 US disclosed
EP-1311257-B1 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INC (US) 2005-04-27 EP disclosed
EP-1311258-B1 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INC (US) 2005-04-06 EP disclosed
US-20020058707-A1 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED 2002-05-16 US disclosed
US-20020058701-A1 Compositions containing hypoglycemically active stilbenoids SHAMAN PHARMACEUTICALS 2002-05-16 US disclosed
US-20020055541-A1 Compositions containing hypotriglyceridemically active stilbenoids SHAMAN PHARMACEUTICALS, INC. 2002-05-09 US disclosed
WO-2002013811-A2 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed
WO-2002013809-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed
WO-2002013806-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058707-A1 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS SLC5A2, SLC5A1, SLC2A1 MAOA 1094/4885MAOB 844/4885CYP19A1 207/4885
US-20020055541-A1 Compositions containing hypotriglyceridemically active stilbenoids CPT1B, CPT1A, LIPC MAOA 2321/4885MAOB 1218/4885CYP19A1 618/4885
US-20020058701-A1 Compositions containing hypoglycemically active stilbenoids SLC5A2, SLC5A1, SLC2A1 MAOA 1094/4885MAOB 844/4885CYP19A1 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.