Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232578 | 1.00 | CHRM2 (0.53) | CHRM2CHRM4CHRM1CHRM3SLC18A3 | |
| SCHEMBL6236146 | 0.97 | CHRM2 (0.57) | CHRM2CHRM4CHRM1CHRM3SLC18A3 | |
| SCHEMBL6236142 | 0.97 | CHRM2 (0.57) | CHRM2CHRM4CHRM1CHRM3SLC18A3 | |
| SCHEMBL10907426 | 0.87 | SLC18A3 (0.61) | CHRM2CHRM4CHRM1CHRM3SLC18A3 | |
| SCHEMBL25755470 | 0.87 | SLC18A3 (0.61) | CHRM2CHRM4CHRM1CHRM3SLC18A3 | |
| SCHEMBL1785360 | 0.87 | SLC18A3 (0.61) | CHRM2CHRM4CHRM1CHRM3SLC18A3 | |
| SCHEMBL26710051 | 0.87 | SLC18A3 (0.61) | CHRM2CHRM4CHRM1CHRM3SLC18A3 | |
| SCHEMBL6232026 | 0.83 | ALDH1A1 (0.47) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL6232028 | 0.83 | ALDH1A1 (0.47) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL6235818 | 0.82 | ADRB2 (0.47) | CHRM2CHRM4CHRM1CHRM3SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000855-A1 | PROCESS FOR THE PREPARATION OF ATROPISOMERIC ANALOGUES OF 4-AMINOPYRIDINE | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |