Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390080 | 0.91 | KMT2A (0.65) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL108393 | 0.91 | KMT2A (0.65) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL12613696 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL6233037 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KMT2ASMN1; SMN2MAPTTDP1 | |
| SCHEMBL7359455 | 0.83 | MAPT (0.48) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2468178 | 0.83 | MAPT (0.55) | ALDH1A1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL7389078 | 0.82 | KMT2A (0.47) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL23579411 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL14003611 | 0.82 | ALDH1A1 (0.65) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL14063302 | 0.82 | MAPT (0.54) | ALDH1A1KMT2AMAPTMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |