Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14063302 | 0.86 | MAPT (0.54) | MAPTKMT2AMEN1GFERKAT2B | |
| SCHEMBL108393 | 0.86 | KMT2A (0.65) | MAPTKMT2AMEN1GFERTDP1 | |
| SCHEMBL29390080 | 0.86 | KMT2A (0.65) | MAPTKMT2AMEN1GFERTDP1 | |
| SCHEMBL29375013 | 0.84 | KAT2B (0.58) | MAPTKMT2AMEN1KAT2BPOLB | |
| SCHEMBL502704 | 0.84 | KAT2B (0.58) | MAPTKMT2AMEN1KAT2BPOLB | |
| SCHEMBL6232719 | 0.83 | ALDH1A1 (0.65) | MAPTKMT2AMEN1GFERKAT2B | |
| SCHEMBL10653490 | 0.83 | MEN1 (0.57) | MAPTKMT2AMEN1KAT2BPOLB | |
| SCHEMBL2470932 | 0.83 | KAT2B (0.52) | MAPTKMT2AMEN1KAT2BPOLB | |
| SCHEMBL4978573 | 0.82 | MAPT (0.56) | MAPTKMT2AMEN1GFERKAT2B | |
| SCHEMBL10139198 | 0.82 | MAPT (0.62) | MAPTKMT2AMEN1GFERKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437123-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | claimed |
| EP-0999823-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2011-10-05 | — | — | EP | claimed |
| EP-1437123-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2007-06-06 | — | — | EP | claimed |
| EP-1437123-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| EP-0999823-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-6712861-B2 | CATIONIC DIRECT DYE | L'OREAL S.A. (FR) | 2004-03-30 | — | — | US | claimed |
| US-20030084516-A9 | Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods | L'OREAL S.A. (FR) | 2003-05-08 | — | — | US | claimed |
| US-20030000023-A9 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL S.A. (FR) | 2003-01-02 | — | — | US | claimed |
| US-20020095732-A1 | Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods | KRAVTCHENKO SYLVAIN (FR) | 2002-07-25 | — | — | US | claimed |
| US-20020004956-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | RONDEAU CHRISTINE (FR) | 2002-01-17 | — | — | US | claimed |
| EP-1149575-A1 | Oxidative dyeing composition for keratin fibres comprising 1-(4-aminophenyl)-pyrrolidine and a particular direct dye | L'OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| US-20230139146-A1 | DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE | L'OREAL (FR) | 2023-05-04 | — | — | US | disclosed |
| CN-105828882-B | Packaging article comprising an envelope and an anhydrous dye composition comprising a direct dye, use thereof and process for dyeing keratin fibres | 莱雅公司 | 2022-09-30 | — | — | CN | disclosed |
| US-11166896-B2 | Process for dyeing and relaxing curls of keratin fibres, using reducing agents and hair dyes, and associated kit | L'OREAL (FR) | 2021-11-09 | — | — | US | disclosed |
| EP-3558462-B1 | PROCESS FOR DYEING AND RELAXING CURLS OF KERATIN FIBRES, USING REDUCING AGENTS AND HAIR DYES, AND ASSOCIATED KIT | OREAL (FR) | 2021-01-20 | — | — | EP | disclosed |
| US-20020004956-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | RONDEAU CHRISTINE (FR) | 2002-01-17 | — | — | US | disclosed |
| EP-1149575-A1 | Oxidative dyeing composition for keratin fibres comprising 1-(4-aminophenyl)-pyrrolidine and a particular direct dye | L'OREAL (FR) | 2001-10-31 | — | — | EP | disclosed |
| EP-0999823-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999020235-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 1999-04-29 | — | — | WO | disclosed |
| US-4637821-A | HAIR, DYEING | L'OREAL (FR) | 1987-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030000023-A9 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | KRT18, CYB5R3, TUBB6 | MAPT 834/4885KMT2A 1964/4885MEN1 3003/4885 |
| US-20020095732-A1 | Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods | KRT18, PLOD1, PLOD2 | MAPT 559/4885KMT2A 2071/4885MEN1 3814/4885 |
| US-20230139146-A1 | DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE | KRT18, TPM3, PRKDC | MAPT 904/4885KMT2A 765/4885MEN1 3790/4885 |
| US-20030084516-A9 | Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods | KRT18, PLOD1, PLOD2 | MAPT 559/4885KMT2A 2071/4885MEN1 3814/4885 |
| US-11166896-B2 | Process for dyeing and relaxing curls of keratin fibres, using reducing agents and hair dyes, and associated kit | KRT18, KIT, KLK5 | MAPT 752/4885KMT2A 701/4885MEN1 2579/4885 |
| US-20020004956-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | KRT18, TUBB1, TUBB4B | MAPT 522/4885KMT2A 1572/4885MEN1 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.