Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233685 | 0.91 | PPARG (0.37) | NCEH1LMNATSHRNPC1RAB9A | |
| SCHEMBL5678240 | 0.85 | NCEH1 (0.40) | NCEH1ALOX5ESR1ALDH1A1HPGD | |
| SCHEMBL5680557 | 0.84 | NCEH1 (0.39) | NCEH1ALOX5ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6234840 | 0.84 | ALOX5 (0.47) | NCEH1ALOX5ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5586648 | 0.84 | TYR (0.40) | NCEH1ALOX5HSD17B10TSHRPPARG | |
| SCHEMBL5676413 | 0.82 | PRKCI (0.39) | NCEH1ALOX5ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6232752 | 0.82 | ALOX5 (0.39) | NCEH1ALOX5ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6230577 | 0.82 | CYP1A2 (0.40) | NCEH1HSD17B10LMNATSHRPPARG | |
| SCHEMBL5590140 | 0.82 | AKR1C2 (0.39) | AKR1C2AKR1C1NCEH1ALOX5ESR1 | |
| SCHEMBL5921668 | 0.82 | NCEH1 (0.39) | NCEH1ALOX5ESR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |