Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232359 | 0.91 | MAPT (0.40) | ALOX5PPARAPPARGPPARDLMNA | |
| SCHEMBL6230577 | 0.87 | CYP1A2 (0.40) | PPARAPPARGNCEH1PPARDLMNA | |
| SCHEMBL5678240 | 0.86 | NCEH1 (0.40) | ALOX5PPARAPPARGKDM4ENCEH1 | |
| SCHEMBL6230641 | 0.85 | CYP1A2 (0.44) | PPARAPPARGPPARDLMNATSHR | |
| SCHEMBL5586648 | 0.85 | TYR (0.40) | ALOX5PTGS2PPARAPPARGNCEH1 | |
| SCHEMBL5680557 | 0.85 | NCEH1 (0.39) | ALOX5PTGS2PPARAPPARGKDM4E | |
| SCHEMBL5921668 | 0.84 | NCEH1 (0.39) | ALOX5KDM4ENCEH1ALDH1A1LMNA | |
| SCHEMBL6232752 | 0.84 | ALOX5 (0.39) | ALOX5KDM4ENCEH1ALDH1A1HPGD | |
| SCHEMBL6232728 | 0.84 | AKR1C2 (0.39) | ALOX5PPARAPPARGKDM4ENCEH1 | |
| SCHEMBL5676413 | 0.84 | PRKCI (0.39) | ALOX5PPARAPPARGNCEH1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |