Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727403 | 0.80 | CHRNB2 (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA2 | |
| SCHEMBL6233088 | 0.79 | CHRNB2 (0.40) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA6 | |
| SCHEMBL4779704 | 0.79 | CHRNB2 (0.40) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA6 | |
| SCHEMBL8508215 | 0.79 | CHRNB2 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA6 | |
| SCHEMBL8507735 | 0.78 | CHRNB2 (0.34) | CHRNB2CHRNA6 | |
| SCHEMBL6236214 | 0.77 | CHRNB2 (0.40) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA6 | |
| SCHEMBL6234636 | 0.77 | CHRNB2 (0.50) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA6 | |
| SCHEMBL8550383 | 0.76 | GPR119 (0.37) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL7406929 | 0.76 | CHRNB4 (0.36) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL6233084 | 0.76 | CHRNB2 (0.40) | CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000806-A2 | LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS, AND METHODS OF MAKING AND USING THEM | GEORGETOWN UNIVERSITY (US) | 2005-01-06 | — | — | WO | disclosed |