Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172321 | 0.77 | KDM1A (0.43) | KDM1ASLC6A4TSHRMAPK1SLC6A3 | |
| SCHEMBL10763454 | 0.76 | MAOA (0.33) | KDM1APNMTBACE1BACE2 | |
| SCHEMBL3107125 | 0.70 | KDM1A (0.42) | KDM1ASLC6A4TSHRMAPK1SLC6A3 | |
| SCHEMBL7104862 | 0.69 | MAPT (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL16014198 | 0.69 | KDM1A (0.43) | KDM1ASLC6A4TSHRMAPK1SLC6A3 | |
| SCHEMBL1391271 | 0.68 | DHFR (0.43) | KDM1ASLC6A4TSHRMAPK1BACE1 | |
| SCHEMBL22369879 | 0.67 | KDM1A (0.56) | KDM1ASLC6A4TSHRMAPK1SLC6A3 | |
| SCHEMBL1420518 | 0.66 | KDM1A (0.59) | KDM1ASLC6A4TSHRMAPK1SLC6A3 | |
| Hydrochloric Acid SCHEMBL20564061 | 0.66 | KDM1A (0.54) | KDM1ASLC6A4TSHRMAPK1SLC6A3 | |
| Hydrochloric Acid SCHEMBL3001569 | 0.65 | KDM1A (0.57) | KDM1ASLC6A4TSHRMAPK1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |