Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 7/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860819 | 0.80 | DHFR (0.54) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL6234475 | 0.80 | RPS6KB2 (0.53) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL31393470 | 0.78 | RPS6KB2 (0.74) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL16027135 | 0.78 | RPS6KB2 (0.74) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL6234491 | 0.76 | RPS6KB2 (0.68) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL19066635 | 0.76 | RPS6KB2 (0.71) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| Bromide SCHEMBL19066634 | 0.74 | RPS6KB2 (0.69) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL2858919 | 0.74 | MEN1 (0.61) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL31265460 | 0.74 | RPS6KB2 (0.61) | RPS6KB2RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL578071 | 0.74 | RPS6KB2 (0.61) | RPS6KB2RAB9AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007099-A2 | PKB INHIBITORS AS ANTI-TUMOR AGENTS | IMCLONE SYSTEMS INCORPORATED (US) | 2005-01-27 | — | — | WO | disclosed |