Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428170 | 0.84 | GALR1 (0.37) | GALR1SMN1; SMN2ALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL5032177 | 0.84 | KDM4E (0.40) | GALR1SMN1; SMN2ALDH1A1L3MBTL1PI4KB | |
| SCHEMBL6864393 | 0.82 | DRD2 (0.41) | GALR1 | |
| SCHEMBL5428789 | 0.81 | GALR1 (0.43) | GALR1SMN1; SMN2ALDH1A1L3MBTL1PIK3CA | |
| SCHEMBL6233028 | 0.80 | CYP19A1 (0.41) | GALR1SMN1; SMN2PIK3CADHFRKMT2A | |
| SCHEMBL6016980 | 0.79 | SMN1; SMN2 (0.38) | GALR1SMN1; SMN2L3MBTL1PIK3CAKMT2A | |
| SCHEMBL6607362 | 0.79 | GALR1 (0.39) | GALR1 | |
| SCHEMBL5428655 | 0.78 | GALR1 (0.33) | GALR1SMN1; SMN2PIK3CA | |
| SCHEMBL5554025 | 0.78 | GALR1 (0.38) | GALR1 | |
| SCHEMBL5553539 | 0.77 | DRD2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |