Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | LTC4S | Q16873 | 6/20 | 0.37 |
| ▸ | GALR1 | P47211 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841050 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5555659 | 0.80 | PDGFRB (0.32) | LTC4SGALR1PIK3CA | |
| SCHEMBL6232918 | 0.79 | GALR1 (0.37) | SMN1; SMN2GALR1PIK3CAKMT2AL3MBTL1 | |
| SCHEMBL5032177 | 0.79 | KDM4E (0.40) | SMN1; SMN2GALR1KMT2AMEN1LMNA | |
| SCHEMBL6428170 | 0.79 | GALR1 (0.37) | SMN1; SMN2GALR1FGFR3L3MBTL1FGFR1 | |
| SCHEMBL6853372 | 0.79 | CCNA2 (0.34) | SMN1; SMN2LTC4SGALR1PIK3CAKMT2A | |
| SCHEMBL6233028 | 0.78 | CYP19A1 (0.41) | SMN1; SMN2GALR1PIK3CAKMT2AMEN1 | |
| SCHEMBL6864393 | 0.77 | DRD2 (0.41) | GALR1LMNA | |
| SCHEMBL6819109 | 0.77 | LMNA (0.45) | SMN1; SMN2PIK3CAFGFR3LMNAFGFR1 | |
| SCHEMBL5428789 | 0.75 | GALR1 (0.43) | SMN1; SMN2GALR1PIK3CAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132423-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-11-07 | — | — | US | disclosed |