Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 6/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231278 | 0.90 | PTPRZ1 (0.41) | PTPRZ1PPARDBCHECD274MEN1 | |
| SCHEMBL6232919 | 0.90 | PTPRZ1 (0.44) | PTPRZ1PPARDBCHECD274PDCD1 | |
| SCHEMBL6230537 | 0.85 | BCHE (0.52) | BCHECD274PDCD1MEN1KMT2A | |
| SCHEMBL6236911 | 0.85 | PLK1 (0.48) | BCHEMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6256021 | 0.81 | PTPRZ1 (0.42) | PTPRZ1PPARDCD274PDCD1 | |
| SCHEMBL6232104 | 0.81 | PTPRZ1 (0.42) | PTPRZ1PPARDCD274PDCD1 | |
| SCHEMBL6235290 | 0.80 | PLK1 (0.40) | PTPRZ1BCHECD274MEN1KMT2A | |
| SCHEMBL6271288 | 0.79 | PTPRZ1 (0.38) | PTPRZ1PPARDCD274PDCD1 | |
| SCHEMBL6234948 | 0.79 | PTPRZ1 (0.38) | PTPRZ1PPARDCD274PDCD1 | |
| SCHEMBL6232647 | 0.76 | PDCD1 (0.41) | PTPRZ1CD274PDCD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |