Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232926 | 0.90 | PTPRZ1 (0.42) | PTPRZ1BCHEMEN1KMT2APPARD | |
| SCHEMBL6236432 | 0.85 | BCHE (0.46) | BCHEMEN1KMT2ANPSR1 | |
| SCHEMBL6235290 | 0.85 | PLK1 (0.40) | PTPRZ1PTPN1BCHEMEN1KMT2A | |
| SCHEMBL6231278 | 0.82 | PTPRZ1 (0.41) | PTPRZ1PTPN1BCHEMEN1KMT2A | |
| SCHEMBL6261792 | 0.81 | PTPRZ1 (0.43) | PTPRZ1PTPN1PTPN2PTPN7PPARD | |
| SCHEMBL6232917 | 0.81 | PTPRZ1 (0.43) | PTPRZ1PTPN1PTPN2PTPN7PPARD | |
| SCHEMBL6236911 | 0.79 | PLK1 (0.48) | BCHEMEN1KMT2ALMNANPSR1 | |
| SCHEMBL6231785 | 0.77 | SMN1; SMN2 (0.39) | MEN1KMT2AMAOAMAOBLMNA | |
| SCHEMBL6232647 | 0.76 | PDCD1 (0.41) | PTPRZ1PTPN1MEN1KMT2ALMNA | |
| SCHEMBL6230537 | 0.74 | BCHE (0.52) | BCHEMEN1KMT2ALMNAPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |