Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 10/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 10/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235952 | 0.87 | PDCD1 (0.51) | PDCD1CD274KDM4EMEN1LMNA | |
| SCHEMBL6235290 | 0.85 | PLK1 (0.40) | CD274PTPRZ1PTPN1MAPTKDM4E | |
| SCHEMBL6236911 | 0.85 | PLK1 (0.48) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL6235743 | 0.82 | PDCD1 (0.39) | PDCD1CD274PTPRZ1MAPTKDM4E | |
| SCHEMBL6271865 | 0.79 | SMN1; SMN2 (0.47) | PDCD1CD274MAPTKDM4EMEN1 | |
| SCHEMBL6231278 | 0.78 | PTPRZ1 (0.41) | CD274PTPRZ1PTPN1MEN1KMT2A | |
| SCHEMBL6232926 | 0.76 | PTPRZ1 (0.42) | PDCD1CD274PTPRZ1KDM4EMEN1 | |
| SCHEMBL6232919 | 0.76 | PTPRZ1 (0.44) | PDCD1CD274PTPRZ1PTPN1MEN1 | |
| SCHEMBL6233816 | 0.72 | SLC2A1 (0.51) | CD274KDM4EMEN1LMNAKMT2A | |
| SCHEMBL6688691 | 0.72 | PDCD1 (0.44) | PDCD1CD274MAPTLMNACTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |