Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5398801 | 0.94 | KMT2A (0.54) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL5399437 | 0.94 | KMT2A (0.59) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL5416796 | 0.93 | KMT2A (0.53) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL5402445 | 0.92 | TDP1 (0.52) | KMT2AMEN1ALDH1A1HSP90AA1TDP1 | |
| SCHEMBL5406393 | 0.91 | KMT2A (0.64) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL5399239 | 0.90 | CA12 (0.55) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL5402294 | 0.90 | LTB4R (0.49) | KMT2AMEN1ALDH1A1HPGDNPC1 | |
| SCHEMBL5400721 | 0.89 | KMT2A (0.51) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL5405330 | 0.89 | KMT2A (0.55) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL5392897 | 0.88 | KMT2A (0.50) | KMT2AMEN1ALDH1A1HPGDTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1533294-A1 | BETA-ALANINE DERIVATIVE AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-05-25 | — | — | EP | disclosed |