Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411854 | 0.90 | TSHR (0.48) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL5405324 | 0.89 | TSHR (0.59) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL6232981 | 0.89 | KMT2A (0.60) | KMT2AMEN1ALDH1A1TDP1TACR1 | |
| SCHEMBL5409458 | 0.88 | TSHR (0.46) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL5402261 | 0.87 | KMT2A (0.50) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL5401137 | 0.87 | LTB4R2 (0.49) | KMT2ATSHRMAPK1 | |
| SCHEMBL5398801 | 0.86 | KMT2A (0.54) | KMT2AMEN1ALDH1A1TDP1TACR1 | |
| SCHEMBL5399437 | 0.85 | KMT2A (0.59) | KMT2AMEN1ALDH1A1TDP1TACR1 | |
| SCHEMBL5405895 | 0.85 | HCRTR1 (0.39) | KMT2AMEN1ALDH1A1TDP1TACR1 | |
| SCHEMBL5406393 | 0.85 | KMT2A (0.64) | KMT2AMEN1ALDH1A1TDP1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285680-B2 | β-alanine derivatives and the use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1533294-A1 | BETA-ALANINE DERIVATIVE AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | TGFB1, PML, APOB | KMT2A 2451/4885MEN1 891/4885ALDH1A1 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.