Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233101 | 1.00 | HTT (0.45) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL18764829 | 0.83 | HTT (0.45) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL28231758 | 0.77 | HTT (0.46) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL28230784 | 0.76 | HTT (0.45) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL28231799 | 0.75 | HTT (0.47) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL18765356 | 0.74 | HTT (0.43) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL18764623 | 0.73 | HTT (0.43) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL19229495 | 0.71 | HTT (0.46) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL14737595 | 0.70 | HTT (0.43) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL14744109 | 0.70 | HTT (0.43) | HTTNPSR1ALDH1A1GFERTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |