Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230845 | 0.86 | L3MBTL1 (0.41) | HTTGFEREPHX1MAN2B1NAMPT | |
| SCHEMBL14744109 | 0.83 | HTT (0.43) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL14737595 | 0.83 | HTT (0.43) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL28231758 | 0.77 | HTT (0.46) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL6233101 | 0.76 | HTT (0.45) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL6233102 | 0.76 | HTT (0.45) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL28231799 | 0.75 | HTT (0.47) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL18765356 | 0.74 | HTT (0.43) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL18764829 | 0.73 | HTT (0.45) | HTTNPSR1ALDH1A1GFERTDP1 | |
| SCHEMBL18764623 | 0.73 | HTT (0.43) | HTTNPSR1ALDH1A1GFERTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290878-A | NOVEL FERROPORTIN INHIBITORS | 威佛（国际）股份公司 | 2018-07-17 | — | — | CN | disclosed |