Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.57 |
| ▸ | TUBB | P07437 | 8/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014958 | 0.89 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8134079 | 0.86 | CYP1A2 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12116692 | 0.84 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15870034 | 0.84 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10372518 | 0.84 | TSHR (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL635552 | 0.82 | RECQL (0.56) | LMNA | |
| SCHEMBL1308823 | 0.81 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL212051 | 0.80 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9162777 | 0.80 | MAPT (0.52) | LMNAMAPT | |
| SCHEMBL1306941 | 0.80 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140329863-A1 | NOVEL ANTIPRION COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-06 | — | — | US | disclosed |
| US-20140329863-A1 | NOVEL ANTIPRION COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-06 | — | — | US | disclosed |
| EP-1523556-A1 | METHODS OF TREATING CONDITIONS ASSOCIATED WITH AN EDG-1 RECEPTOR | SRI INTERNATIONAL (US) | 2005-04-20 | — | — | EP | disclosed |
| US-20040147562-A1 | Methods of treating conditions associated with an EDG-1 receptor | MANIV ENERGY CAPITAL | 2004-07-29 | — | — | US | disclosed |
| WO-2004009816-A1 | METHODS OF TREATING CONDITIONS ASSOCIATED WITH AN EDG-1 RECEPTOR | CERETEK LLC (US) | 2004-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147562-A1 | Methods of treating conditions associated with an EDG-1 receptor | EDNRA, EDNRB, ESRRG | TUBB4A 2575/4885TUBB 2332/4885TUBA3C 3444/4885 |
| US-20140329863-A1 | NOVEL ANTIPRION COMPOUNDS | PRNP, PSEN1, PSEN2 | TUBB4A 677/4885TUBB 782/4885TUBA3C 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.