Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5587475 | 0.91 | ALOX5 (0.43) | ALOX5HCAR2HCAR3NPC1HPGD | |
| SCHEMBL6231392 | 0.91 | LDHA (0.36) | ALOX5HCAR2LTB4RLTB4R2 | |
| SCHEMBL5588845 | 0.87 | ALOX5 (0.49) | ALOX5HCAR2HCAR3ESR1AKR1C4 | |
| SCHEMBL5589714 | 0.86 | ALOX5 (0.51) | ALOX5HCAR2HCAR3ESR1AKR1C4 | |
| SCHEMBL5587274 | 0.86 | ALOX5 (0.51) | ALOX5HCAR2HCAR3ESR1AKR1C4 | |
| SCHEMBL5589440 | 0.86 | ALOX5 (0.51) | ALOX5HCAR2HCAR3ESR1AKR1C4 | |
| SCHEMBL5588670 | 0.86 | ALOX5 (0.51) | ALOX5HCAR2HCAR3ESR1AKR1C4 | |
| SCHEMBL5589780 | 0.86 | ALOX5 (0.51) | ALOX5HCAR2HCAR3ESR1AKR1C4 | |
| SCHEMBL5588399 | 0.82 | LDHA (0.38) | ALOX5HCAR2FFAR1LTB4RLTB4R2 | |
| SCHEMBL6232752 | 0.81 | ALOX5 (0.39) | ALOX5HCAR2HCAR3NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |