Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763997 | 0.86 | RIPK1 (0.81) | RIPK1GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL15693637 | 0.81 | HTT (0.69) | MAPTALDH1A1LMNANPC1HTT | |
| SCHEMBL27203243 | 0.80 | RIPK1 (0.60) | RIPK1GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL6233917 | 0.79 | MAPT (0.56) | GRIN1GRIN2BMEN1KMT2AMAPT | |
| SCHEMBL28777311 | 0.78 | GAA (0.69) | GRIN1GRIN2BMAPTKDM4ENPC1 | |
| SCHEMBL29725740 | 0.78 | GAA (0.69) | GRIN1GRIN2BMAPTKDM4ENPC1 | |
| SCHEMBL14837394 | 0.77 | GRIN1 (0.60) | RIPK1GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL10475710 | 0.76 | RIPK1 (0.61) | RIPK1GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL31154045 | 0.76 | GRIN1 (0.62) | RIPK1GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL8027000 | 0.76 | RIPK1 (0.58) | RIPK1GRIN1GRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |