Sugi Predict

Sugi Predict / Compounds / SCHEMBL6233405

SCHEMBL6233405

SCHEMBL6233405

COc1ncnc(N)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDE5A O76074 1/20 0.46
▸ ESR1 P03372 1/20 0.44
▸ PDPK1 O15530 1/20 0.38
▸ MAP4K4 O95819 3/20 0.35
▸ LCK P06239 1/20 0.34
▸ PI4KB Q9UBF8 3/20 0.34
▸ KDR P35968 2/20 0.34
▸ PIK3CD O00329 1/20 0.34
▸ ABL1 P00519 1/20 0.34
▸ EGFR P00533 1/20 0.34
▸ HCK P08631 1/20 0.34
▸ SRC P12931 1/20 0.34
▸ PIK3CA P42336 1/20 0.34
▸ PIK3CB P42338 1/20 0.34
▸ MTOR P42345 1/20 0.34
▸ PIK3CG P48736 1/20 0.34
▸ EPHB4 P54760 1/20 0.34
▸ PRKDC P78527 1/20 0.34
▸ PI4KA P42356 2/20 0.33
▸ PI4K2B Q8TCG2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3817132 0.83 PDPK1 (0.45) PDE5AESR1PDPK1LCKMAPT
SCHEMBL28404190 0.79 PDE5A (0.38) PDE5AESR1KDRFYNRET
SCHEMBL11475921 0.79 PDPK1 (0.39) PDE5AESR1PDPK1MAP4K4PI4KB
SCHEMBL29636952 0.77 PDE5A (0.46) PDE5AMAP4K4PI4KBKDRPIK3CD
SCHEMBL179602 0.77 LIMK1 (0.38) PDE5AESR1PDPK1MAP4K4PI4KB
SCHEMBL16712814 0.77 PDE5A (0.46) PDE5AMAP4K4PI4KBKDRPIK3CD
SCHEMBL1872205 0.76 PDE5A (0.49) PDE5AMAP4K4PI4KBKDRPIK3CD
SCHEMBL38661744 0.76 PDPK1 (0.37) PDE5AESR1PDPK1MAP4K4PI4KB
SCHEMBL15334043 0.76 PDPK1 (0.37) PDE5AESR1PDPK1MAP4K4PI4KB
SCHEMBL2900733 0.75 PDPK1 (0.43) PDE5AESR1PDPK1MAP4K4RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114778711-A Method for analyzing related substances of sulfadoxine 江苏金申医药科技有限公司 2022-07-22 — — CN claimed
EP-1529036-A1 METHOD FOR PRODUCING HIGHLY PURE CRYSTALLINE 4-AMINO-5,6-DIMETHOXYPYRIMIDINE Degussa AG (DE) 2005-05-11 — — EP claimed
WO-2004007466-A1 METHOD FOR PRODUCING HIGHLY PURE CRYSTALLINE 4-AMINO-5,6-DIMETHOXYPYRIMIDINE DEGUSSA AG (DE) 2004-01-22 — — WO claimed
CN-114778711-A Method for analyzing related substances of sulfadoxine 江苏金申医药科技有限公司 2022-07-22 — — CN disclosed
CN-114778711-A Method for analyzing related substances of sulfadoxine 江苏金申医药科技有限公司 2022-07-22 — — CN disclosed
US-9272902-B2 Resistance heating composition, heating composite using the composition, method of preparing the heating composite, and heating apparatus and fusing apparatus using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-01 — — US disclosed
US-20130222510-A1 RESISTANCE HEATING COMPOSITION, HEATING COMPOSITE USING THE COMPOSITION, METHOD OF PREPARING THE HEATING COMPOSITE, AND HEATING APPARATUS AND FUSING APPARATUS USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-08-29 — — US disclosed
EP-1529036-A1 METHOD FOR PRODUCING HIGHLY PURE CRYSTALLINE 4-AMINO-5,6-DIMETHOXYPYRIMIDINE Degussa AG (DE) 2005-05-11 — — EP disclosed
EP-1529036-A1 METHOD FOR PRODUCING HIGHLY PURE CRYSTALLINE 4-AMINO-5,6-DIMETHOXYPYRIMIDINE Degussa AG (DE) 2005-05-11 — — EP disclosed
WO-2004007466-A1 METHOD FOR PRODUCING HIGHLY PURE CRYSTALLINE 4-AMINO-5,6-DIMETHOXYPYRIMIDINE DEGUSSA AG (DE) 2004-01-22 — — WO disclosed
WO-2004007466-A1 METHOD FOR PRODUCING HIGHLY PURE CRYSTALLINE 4-AMINO-5,6-DIMETHOXYPYRIMIDINE DEGUSSA AG (DE) 2004-01-22 — — WO disclosed