Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 4/20 | 0.38 |
| ▸ | GALR2 | O43603 | 4/20 | 0.36 |
| ▸ | AXL | P30530 | 3/20 | 0.36 |
| ▸ | INSR | P06213 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549889 | 0.91 | GALR1 (0.45) | GALR1GALR2AXLINSRKDR | |
| SCHEMBL5553491 | 0.88 | GALR1 (0.46) | GALR1GALR2AXLINSRKDR | |
| SCHEMBL6429807 | 0.87 | HTT (0.39) | GALR1L3MBTL1EGFRCYP2D6CYP2C19 | |
| SCHEMBL6428940 | 0.85 | PIK3CA (0.38) | — | |
| SCHEMBL6233437 | 0.84 | GALR1 (0.46) | GALR1GALR2CDK4CCND1CDK1 | |
| SCHEMBL6229485 | 0.84 | GALR1 (0.41) | GALR1GALR2AXLINSRKDR | |
| SCHEMBL6429951 | 0.83 | GALR1 (0.42) | GALR1GALR2AXLINSRKDR | |
| SCHEMBL6273065 | 0.81 | GALR1 (0.41) | GALR1GALR2AXLINSRKDR | |
| SCHEMBL6608904 | 0.81 | GALR1 (0.43) | GALR1GALR2AXLINSRKDR | |
| SCHEMBL5550316 | 0.81 | GALR1 (0.43) | GALR1GALR2AXLINSRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |