Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | CYBB | P04839 | 3/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.34 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.34 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549889 | 0.88 | GALR1 (0.45) | MAPTMAPK1L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL6233417 | 0.87 | GALR1 (0.38) | MAPTL3MBTL1CYP2D6CYP2C19KDM4E | |
| SCHEMBL6428940 | 0.85 | PIK3CA (0.38) | — | |
| SCHEMBL5553491 | 0.84 | GALR1 (0.46) | GALR1 | |
| SCHEMBL6427917 | 0.83 | PIK3CD (0.31) | — | |
| SCHEMBL6229485 | 0.81 | GALR1 (0.41) | CRHR1GALR1 | |
| SCHEMBL6233437 | 0.81 | GALR1 (0.46) | CRHR1GALR1 | |
| SCHEMBL6429951 | 0.80 | GALR1 (0.42) | MAPTMAPK1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL6239105 | 0.80 | HTT (0.44) | HTTMAPTMAPK1TDP1CYBB | |
| SCHEMBL6273065 | 0.78 | GALR1 (0.41) | MAPTL3MBTL1CYP2D6CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124619-A1 | Medical devices employing triazine compounds and compositions thereof | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124619-A1 | Medical devices employing triazine compounds and compositions thereof | PTGIS, AREG, TGFB1 | HTT 648/4885MAPT 3475/4885MAPK1 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.