Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943038 | 0.81 | ALDH1A1 (0.48) | THRBTSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11222212 | 0.80 | CYP2D6 (0.55) | THRBTSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL6547127 | 0.80 | THRB (0.47) | THRBTSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL6547117 | 0.80 | THRB (0.47) | THRBTSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL28136750 | 0.78 | THRB (0.40) | THRBTSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL28707230 | 0.78 | THRB (0.46) | THRBTSHRCYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL1004834 | 0.77 | TSHR (0.62) | THRBTSHRCYP2D6CYP2C19ALDH1A1 | |
| Methacrylic Acid SCHEMBL27774018 | 0.76 | CYP2D6 (0.31) | CYP2D6CYP2C19 | |
| SCHEMBL5680588 | 0.76 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11424882 | 0.75 | TSHR (0.73) | THRBTSHRCYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000980-A2 | PAINT FORMULATION FOR A LOW SURFACE ENERGY SUBSTRATE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040259990-A1 | Paint formulation for a low surface energy substrate | SONNENSCHEIN MARK F (US) | 2004-12-23 | — | — | US | disclosed |