Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 3/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977014 | 0.83 | SMN1; SMN2 (0.66) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9628683 | 0.82 | KMT2A (0.81) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1491507 | 0.81 | POLB (0.63) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL312150 | 0.80 | POLB (0.66) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL16398721 | 0.80 | SMN1; SMN2 (0.62) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5439326 | 0.80 | SMN1; SMN2 (0.62) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL312497 | 0.79 | POLB (0.69) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23612325 | 0.79 | POLB (0.61) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17325491 | 0.78 | LMNA (0.69) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18975725 | 0.78 | LMNA (0.69) | KMT2AHPGDCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |