SCHEMBL6233588

SCHEMBL6233588

CCCCc1nc(SC)c(OC(=O)OCC)n1Cc1cccc(Cc2cccc(S(N)(=O)=O)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 6/20 0.39
AGTR1 P30556 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6229944 0.96 AGTR2 (0.41) AGTR2AGTR1
SCHEMBL8641025 0.89 AGTR2 (0.44) AGTR2AGTR1
SCHEMBL6252410 0.88 AGTR2 (0.39) AGTR2AGTR1
SCHEMBL7262013 0.87 AGTR1 (0.44) AGTR2AGTR1
SCHEMBL6230873 0.86 AGTR2 (0.37) AGTR2AGTR1
SCHEMBL6254461 0.84 AGTR2 (0.41) AGTR2AGTR1
SCHEMBL8637352 0.83 AGTR2 (0.45) AGTR2AGTR1
SCHEMBL7266445 0.83 AGTR1 (0.47) AGTR2AGTR1
SCHEMBL6231351 0.83 AGTR2 (0.39) AGTR2AGTR1
SCHEMBL8653886 0.81 AGTR2 (0.40) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1076651-B1 SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT AVENTIS PHARMA GMBH (DE) 2005-04-20 EP disclosed
EP-1076651-A1 SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT Aventis Pharma Deutschland GmbH (DE) 2001-02-21 EP disclosed
WO-1999057102-A1 SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 1999-11-11 WO disclosed