SCHEMBL6233608

SCHEMBL6233608

O=C(O)c1ccc(Cl)cc1Cl.[NaH]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.95
CASP1 P29466 1/20 0.95
SMN1; SMN2 Q16637 1/20 0.95
ALDH1A1 P00352 3/20 0.65
TP53 P04637 1/20 0.65
SRD5A2 P31213 1/20 0.61
MAPK1 P28482 1/20 0.59
HIF1A Q16665 1/20 0.59
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
KDM4E B2RXH2 1/20 0.57
MAPT P10636 1/20 0.57
ERCC5 P28715 1/20 0.56
FEN1 P39748 1/20 0.56
PPARG P37231 1/20 0.53
PPARA Q07869 1/20 0.53
AKR1C4 P17516 1/20 0.52
AKR1C3 P42330 1/20 0.52
AKR1C2 P52895 1/20 0.52
AKR1C1 Q04828 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111279 0.98 TSHR (1.00) TSHRCASP1SMN1; SMN2ALDH1A1TP53
SCHEMBL28852873 0.95 TSHR (0.95) TSHRCASP1SMN1; SMN2ALDH1A1TP53
Ammonia Solution, Strong SCHEMBL4373474 0.95 TSHR (0.95) TSHRCASP1SMN1; SMN2ALDH1A1TP53
SCHEMBL1151260 0.95 TSHR (0.95) TSHRCASP1SMN1; SMN2ALDH1A1TP53
SCHEMBL1303476 0.95 TSHR (0.95) TSHRCASP1SMN1; SMN2ALDH1A1TP53
Hydrochloric Acid SCHEMBL9651764 0.95 TSHR (0.95) TSHRCASP1SMN1; SMN2ALDH1A1TP53
Acetonitrile SCHEMBL28488651 0.86 TSHR (0.78) TSHRCASP1SMN1; SMN2ALDH1A1TP53
Thioglycolic Acid SCHEMBL8860110 0.86 SMN1; SMN2 (0.78) TSHRCASP1SMN1; SMN2ALDH1A1TP53
Benzoic Acid SCHEMBL8021112 0.86 TSHR (0.78) TSHRCASP1SMN1; SMN2ALDH1A1TP53
SCHEMBL8860105 0.85 SMN1; SMN2 (0.75) TSHRCASP1SMN1; SMN2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433069-A Preparation method of 2, 4-dichlorobenzaldehyde 柳州东风容泰化工股份有限公司 2022-12-06 CN claimed
CN-108455782-B A kind of processing method of bis- (2,4 dichloro benzene formyl) waste water of peroxidating 江苏强盛功能化学股份有限公司 2019-11-29 CN claimed
EP-1214378-B1 FLAME RETARDANT POLYCARBONATE COMPOSITION BAYER AG (US) 2005-04-06 EP claimed
CN-1142981-C Flame retardant polycarbonate composition 美国拜尔公司 2004-03-24 CN claimed
CN-1367807-A Flame retardant polycarbonate composition BAYER AG (US) 2002-09-04 CN claimed
EP-1214378-A1 FLAME RETARDANT POLYCARBONATE COMPOSITION Bayer Corporation (US) 2002-06-19 EP claimed
WO-2001010957-A1 FLAME RETARDANT POLYCARBONATE COMPOSITION BAYER CORPORATION (US) 2001-02-15 WO claimed
US-6180702-B1 A BLENDS COMPRISING POLYALKYL METHACRYLATE WITH FLUORINATED POLYOLEFIN, AND THE SALT SELECT FROM AN ALKALI METAL OR ALKALINE EARTH METAL SALT OF PERFLUOROALKANE SULFONIC ACID, AROMATIC SULFIMIDE, OR AROMATIC SULFONIC ACID BAYER CORPORATION 2001-01-30 US claimed
CN-115433069-A Preparation method of 2, 4-dichlorobenzaldehyde 柳州东风容泰化工股份有限公司 2022-12-06 CN disclosed
US-11472099-B2 Method for producing an object by means of an additive manufacturing process using a polycarbonate building material with improved flowability COVESTRO DEUTSCHLAND AG (DE) 2022-10-18 US disclosed
CN-110267798-B Method of manufacturing an object by additive manufacturing using a polycarbonate build material having improved flow capability 科思创德国股份有限公司 2022-05-27 CN disclosed
CN-112851495-A Treatment method of paste diacyl peroxide 常熟市滨江化工有限公司 2021-05-28 CN disclosed
CN-107207864-B Flame-resistant moulding compositions containing glass fibres, containing silicone-containing polycarbonate block cocondensates 科思创德国股份有限公司 2021-03-02 CN disclosed
CN-107207863-B Flame-resistant moulding compositions containing silicone-containing polycarbonate block cocondensates 科思创德国股份有限公司 2021-02-19 CN disclosed
US-4534875-A REACTION PRODUCT OF HYDROPHOBIC HYDROPHILIC SURFACTANT AND ELECTROLYTE THE DOW CHEMICAL COMPANY (US) 1985-08-13 US disclosed
WO-1985003083-A1 A METHOD FOR CONTROLLING THE OVERALL HEAT TRANSFER COEFFICIENT OF A HEAT EXCHANGE FLUID THE DOW CHEMICAL COMPANY (US) 1985-07-18 WO disclosed
EP-0092581-A4 FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. DOW CHEMICAL CO (US) 1984-03-29 EP disclosed
EP-0092581-A1 FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. DOW CHEMICAL CO (US) 1983-11-02 EP disclosed
WO-1983001583-A1 FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT DOW CHEMICAL CO (US) 1983-05-11 WO disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed