SCHEMBL2901464

SCHEMBL2901464

NC[C@H]1CN(c2cc(F)cc(F)c2)C(=O)O1

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.52
GRM2 Q14416 7/20 0.48
CALML3 P27482 3/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 1/20 0.42
FADS1 O60427 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2896810 1.00 F10 (0.52) F10GRM2CALML3MAOAMAOB
SCHEMBL6233611 0.85 GRM2 (0.66) F10GRM2CALML3MAOAMAOB
SCHEMBL2896939 0.85 GRM2 (0.66) F10GRM2CALML3MAOAMAOB
SCHEMBL3430334 0.84 MAOA (0.58) GRM2CALML3MAOAMAOBFADS1
SCHEMBL3430331 0.84 MAOA (0.58) GRM2CALML3MAOAMAOBFADS1
SCHEMBL8594735 0.84 GRM2 (0.48) F10GRM2CALML3MAOAMAOB
SCHEMBL12956131 0.84 F10 (0.49) F10GRM2CALML3MAOAMAOB
SCHEMBL3368977 0.84 F10 (0.49) F10GRM2CALML3MAOAMAOB
SCHEMBL3368973 0.84 F10 (0.49) F10GRM2CALML3MAOAMAOB
SCHEMBL16701334 0.81 BPTF (0.57) F10GRM2CALML3MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD F10 1709/4885GRM2 3646/4885CALML3 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.