Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157041 | 0.74 | KDM4E (0.70) | MAOAMAOBKDM4EHTTL3MBTL1 | |
| SCHEMBL178579 | 0.74 | MAOA (0.48) | MAOAMAOBACHEBACE1KDM4E | |
| Hydrochloric Acid SCHEMBL29089156 | 0.73 | KDM4E (0.52) | MAOAMAOBKDM4EHTTL3MBTL1 | |
| SCHEMBL4292799 | 0.73 | KDM4E (0.68) | MAOAMAOBKDM4EHTTL3MBTL1 | |
| SCHEMBL10156186 | 0.73 | KDM4E (0.73) | MAOAMAOBKDM4EHTTL3MBTL1 | |
| SCHEMBL112199 | 0.73 | MAOA (0.80) | MAOAMAOBACHEBACE1KDM4E | |
| SCHEMBL15854518 | 0.72 | KDM4E (0.77) | MAOAMAOBKDM4EHTTL3MBTL1 | |
| SCHEMBL2523682 | 0.72 | KDM4E (0.62) | MAOAMAOBACHEBACE1KDM4E | |
| SCHEMBL16407906 | 0.72 | KDM4E (0.66) | MAOAMAOBKDM4EHTTL3MBTL1 | |
| SCHEMBL620669 | 0.72 | MAOA (1.00) | MAOAMAOBACHEBACE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603492-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | Varinel Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020389-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | VARINEL INC (US) | 2012-02-16 | — | — | WO | disclosed |