Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044727 | 0.89 | CTSK (0.38) | CTSKCTSSCTSLCTSV | |
| SCHEMBL4043653 | 0.82 | CTSK (0.66) | CTSKCTSSCTSLCTSVALDH1A1 | |
| SCHEMBL4043434 | 0.82 | CTSK (0.48) | CTSKCTSSCTSLCTSVHTRA1 | |
| SCHEMBL4046471 | 0.81 | CTSK (0.47) | CTSKCTSSCTSLALDH1A1 | |
| SCHEMBL4040702 | 0.80 | CTSK (0.38) | CTSKCTSSCTSLUSP30 | |
| SCHEMBL4041899 | 0.80 | CTSK (0.39) | CTSKCTSSCTSLPREPFAP | |
| SCHEMBL4049935 | 0.80 | CTSK (0.53) | CTSKCTSSCTSLCTSVALDH1A1 | |
| SCHEMBL6211281 | 0.79 | CTSK (0.38) | CTSKCTSSCTSLALDH1A1GAA | |
| SCHEMBL4041496 | 0.78 | CTSK (0.40) | CTSKCTSSCTSLALDH1A1 | |
| SCHEMBL4048681 | 0.78 | CTSL (0.32) | CTSKCTSSCTSLCTSVUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |