Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721881 | 0.87 | HNF4A (0.41) | HNF4AGABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL21856951 | 0.85 | HNF4A (0.45) | HNF4AGABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7728547 | 0.83 | NQO2 (0.39) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL5012566 | 0.82 | RXRB (0.40) | HNF4AGABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL7605479 | 0.82 | ALDH1A1 (0.47) | HNF4AALDH1A1CYP1A2CA12CA1 | |
| SCHEMBL31064115 | 0.81 | HNF4A (0.38) | HNF4AGABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL17672806 | 0.77 | ALDH1A1 (0.49) | HNF4AALDH1A1TSHR | |
| SCHEMBL1805369 | 0.77 | KMT2A (0.49) | HNF4AGABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL6231684 | 0.77 | HNF4A (0.42) | HNF4AGABRA1GABRA5GABRG2GABRB3 | |
| SCHEMBL13283750 | 0.74 | MAP2K1 (0.51) | CYP1A2MAP2K1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080368-B1 | MOLECULAR ROD AND USES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2005-05-04 | — | — | EP | disclosed |
| EP-1080368-A1 | MOLECULAR ROD AND USES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999061912-A1 | MOLECULAR ROD AND USES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1999-12-02 | — | — | WO | disclosed |