Ethylene Glycol

Ethylene Glycol

SCHEMBL623373

CN(C)CCCOCCCN(C)C.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
KDM4E B2RXH2 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
HRH3 Q9Y5N1 2/20 0.36
DNM1 Q05193 2/20 0.36
LSS P48449 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7777520 0.92 TSHR (0.54) MAPTTSHRALDH1A1MEN1KMT2A
SCHEMBL17807206 0.90 MEN1 (0.52) MAPTTSHRALDH1A1MEN1KMT2A
SCHEMBL9650360 0.90 MAPT (0.43) MAPTTSHRALDH1A1MEN1KMT2A
SCHEMBL530011 0.89 ALDH1A1 (0.53) TSHRALDH1A1KDM4ESMN1; SMN2CA12
Bromide SCHEMBL28986417 0.86 MAPT (0.43) MAPTTSHRALDH1A1MEN1KMT2A
SCHEMBL9651294 0.86 ALDH1A1 (0.50) TSHRALDH1A1KDM4ESMN1; SMN2CA12
SCHEMBL623374 0.86 ALDH1A1 (0.50) TSHRALDH1A1KDM4ESMN1; SMN2CA12
SCHEMBL10566857 0.86 ALDH1A1 (0.50) TSHRALDH1A1KDM4ESMN1; SMN2CA12
SCHEMBL10881266 0.85 TSHR (0.52) MAPTTSHRALDH1A1MEN1KMT2A
SCHEMBL10402080 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1433832-B1 PHOSPHORUS-CONTAINING CARBOXYLIC ACID DERIVATIVES,PROCESS FOR PREPARATION THEREOF, AND FLAME RETARDANTS NOF CORP (JP) 2013-11-13 EP disclosed
WO-2012020029-A1 POLYURETHANE COMPOSITION FOR INTEGRAL SKIN FOAM BAYER MATERIALSCIENCE AG (DE) 2012-02-16 WO disclosed
US-7429623-B2 Macromer forming catalysts JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-09-30 US disclosed
US-7186784-B2 Phosphorus-containing carboxylic acid derivatives process for preparations thereof and flame retardant NOF CORPORATION (JP) 2007-03-06 US disclosed
EP-1158006-B1 POLYMER, PROCESS FOR PRODUCING THE POLYMER, AND CURABLE COMPOSITION CONTAINING THE POLYMER KANEKA CORP (JP) 2006-11-15 EP disclosed
US-20060004119-A1 Macromer forming catalysts JOHNSON & JOHNSON VISION CARE, INC. 2006-01-05 US disclosed
EP-1534759-A1 MACROMER FORMING CATALYSTS Johnson & Johnson Vision Care, Inc. (US) 2005-06-01 EP disclosed
US-6887936-B2 Polymer, process for producing the polymer, and curable composition containing the polymer KANEKA CORPORATION (JP) 2005-05-03 US disclosed
EP-1024153-B1 POLYMER, PROCESS FOR PRODUCING THE POLYMER, AND CURABLE COMPOSITION CONTAINING THE POLYMER KANEKA CORP (JP) 2005-02-16 EP disclosed
US-6855780-B1 Polymer, process for producing the polymer, and curable composition containing the polymer KANEKA CORPORATION (JP) 2005-02-15 US disclosed
WO-2004000888-A1 MACROMER FORMING CATALYSTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-12-31 WO disclosed
US-20030065100-A1 Polymer, process for producing the polymer, and curable composition containing the polymer KANEKA CORPORATION (JP) 2003-04-03 US disclosed
US-6482900-B1 Polymer, process for producing the polymer, and curable composition containing the polymer KANEKA CORPORATION (JP) 2002-11-19 US disclosed
EP-1158006-A1 POLYMER, PROCESS FOR PRODUCING THE POLYMER, AND CURABLE COMPOSITION CONTAINING THE POLYMER KANEKA CORPORATION (JP) 2001-11-28 EP disclosed
US-6194516-B1 CURED PRODUCT FOR THE APPLICATION OF SEALANT, ADHESIVE, TACKIFIER OR ELASTIC ADHESIVE KANEKA CORPORATION (JP) 2001-02-27 US disclosed
EP-1024153-A1 POLYMER, PROCESS FOR PRODUCING THE POLYMER, AND CURABLE COMPOSITION CONTAINING THE POLYMER KANEKA CORPORATION (JP) 2000-08-02 EP disclosed
US-6075065-A COMPRISES A POLYURETHANE (METH)ACRYLATE OLIGOMER, AN ETHYLENICALLY UNSATURATED COMPOUND, A BISACYLPHOSPHINE OXIDE-SERIES PHOTOPOLYMERIZATION INITIATOR, AND A TERTIARY AMINE AND NO TIN COMPONENT TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-06-13 US disclosed
US-5852129-A Method for producing hydroxyl-terminated (meth) acrylic polymer KANEKA CORPORATION (JP) 1998-12-22 US disclosed
EP-0849296-A2 A photocurable resin composition and a method for producing the same TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-24 EP disclosed
EP-0845479-A2 Method for producing hydroxyl-terminated (meth)acrylic polymer, the said polymer KANEKA CORPORATION (JP) 1998-06-03 EP disclosed