Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28986417 | 0.96 | MAPT (0.43) | MAPTMEN1THRBHTTKMT2A | |
| SCHEMBL7349480 | 0.93 | TSHR (0.50) | MAPTMEN1THRBHTTKMT2A | |
| Ethylene Glycol SCHEMBL623373 | 0.90 | MAPT (0.48) | MAPTMEN1THRBHTTKMT2A | |
| Cetostearyl Alcohol SCHEMBL936994 | 0.90 | MEN1 (0.59) | MAPTMEN1THRBHTTKMT2A | |
| SCHEMBL7777520 | 0.88 | TSHR (0.54) | MAPTMEN1THRBHTTKMT2A | |
| SCHEMBL9651294 | 0.87 | ALDH1A1 (0.50) | TSHRALDH1A1KDM4ESMN1; SMN2LSS | |
| SCHEMBL10881266 | 0.86 | TSHR (0.52) | MAPTMEN1THRBHTTKMT2A | |
| SCHEMBL17807206 | 0.86 | MEN1 (0.52) | MAPTMEN1THRBHTTKMT2A | |
| SCHEMBL22813038 | 0.85 | ALDH1A1 (0.56) | TSHRALDH1A1KDM4ESMN1; SMN2LSS | |
| SCHEMBL530011 | 0.84 | ALDH1A1 (0.53) | TSHRALDH1A1KDM4ESMN1; SMN2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091583-A | Also provides extended pot life | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-02-25 | — | — | US | disclosed |
| US-5071809-A | TERTIARY AMINE CATALYSTS FOR POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0456194-A2 | Tertiary amine catalysts for polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-11-13 | — | — | EP | disclosed |