Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 3/20 | 0.38 |
| ▸ | GALR1 | P47211 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.37 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | CTSH | P09668 | 1/20 | 0.37 |
| ▸ | CASP14 | P31944 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032423 | 0.83 | BCL6 (0.44) | GALR2GALR1CTSLCTSSCTSK | |
| SCHEMBL5030764 | 0.82 | GALR1 (0.40) | GALR2GALR1CTSLCTSSCTSK | |
| Hydrochloric Acid SCHEMBL4838629 | 0.81 | GALR1 (0.39) | GALR2GALR1CTSLCTSSCTSK | |
| SCHEMBL4840203 | 0.81 | IDH2 (0.49) | GALR2GALR1CTSLCTSSCTSK | |
| SCHEMBL6233894 | 0.77 | AURKA (0.33) | CTSLCTSSCTSKCTSVPLAT | |
| SCHEMBL4829410 | 0.73 | IDH2 (0.49) | GALR2GALR1CTSLCTSSCTSK | |
| Hydrochloric Acid SCHEMBL5554300 | 0.71 | IDH2 (0.48) | GALR2GALR1CTSLCTSSCTSK | |
| SCHEMBL4870097 | 0.71 | BCL6 (0.42) | — | |
| Hydrochloric Acid SCHEMBL5431369 | 0.71 | IDH2 (0.47) | GALR2GALR1CTSLCTSSCTSK | |
| SCHEMBL4838644 | 0.70 | IDH2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |