Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032423 | 0.78 | BCL6 (0.44) | SMN1; SMN2CTSVPLATCTSLCTSH | |
| SCHEMBL6233888 | 0.77 | GALR2 (0.38) | CTSVPLATCTSLCTSHCTSS | |
| SCHEMBL5030764 | 0.75 | GALR1 (0.40) | SMN1; SMN2CTSLCTSSCTSK | |
| Hydrochloric Acid SCHEMBL4838629 | 0.74 | GALR1 (0.39) | SMN1; SMN2CTSLCTSSCTSK | |
| SCHEMBL6017078 | 0.64 | MEN1 (0.34) | MAPK8MCHR1SMN1; SMN2ADRA2A | |
| SCHEMBL4870097 | 0.63 | BCL6 (0.42) | AURKAMAP4K4PAK4ABL1LCK | |
| Hydrochloric Acid SCHEMBL4838602 | 0.61 | GALR1 (0.40) | SMN1; SMN2CTSLCTSSCTSK | |
| SCHEMBL4836907 | 0.61 | GALR1 (0.40) | SMN1; SMN2CTSLCTSSCTSK | |
| SCHEMBL4840855 | 0.60 | BCL6 (0.51) | SMN1; SMN2CTSVPLATCTSLCTSH | |
| SCHEMBL5555643 | 0.60 | CCR8 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |