SCHEMBL623392

SCHEMBL623392

CC(C)CC1=CCC(C=O)CC1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP1B1 Q16678 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FNTA P49354 1/20 0.30
PGGT1B P53609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21591813 1.00 CES2 (0.31) CES2ALOX15CYP1B1ALDH1A1NPC1
SCHEMBL5042652 0.80 FNTA (0.44) SMN1; SMN2FNTAPGGT1B
SCHEMBL10708005 0.79 CES2 (0.33) CES2ALOX15CYP1B1ALDH1A1
SCHEMBL8208467 0.77
SCHEMBL21591822 0.76
SCHEMBL4451624 0.75 TRPA1 (0.31)
SCHEMBL14646627 0.74 CES2 (0.33) CES2ALOX15CYP1B1ALDH1A1
SCHEMBL7524327 0.74 CES2 (0.36) CES2ALOX15CYP1B1ALDH1A1NPC1
SCHEMBL28972629 0.74 CES2 (0.33) CES2ALOX15CYP1B1ALDH1A1
SCHEMBL28972631 0.74 CES2 (0.33) CES2ALOX15CYP1B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3807241-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2022-04-13 EP disclosed
US-8999914-B2 Cyclohexene- and cyclopropanated cyclohexene- derivatives as fragrances GIVAUDAN S.A. (CH) 2015-04-07 US disclosed
EP-2603483-B1 CYCLOHEXENE- AND CYCLOPROPANATED CYCLOHEXENE- DERIVATIVES AS FRAGRANCES GIVAUDAN SA (CH) 2015-02-25 EP disclosed
US-20130303433-A1 Cyclohexene- And Cyclopropanated Cyclohexene- Derivatives As Fragrances GIVAUDAN S.A. (CH) 2013-11-14 US disclosed
EP-2603483-A1 CYCLOHEXENE- AND CYCLOPROPANATED CYCLOHEXENE - DERIVATIVES AS FRAGRANCES Givaudan SA (CH) 2013-06-19 EP disclosed
WO-2012020076-A1 CYCLOHEXENE- AND CYCLOPROPANATED CYCLOHEXENE - DERIVATIVES AS FRAGRANCES GIVAUDAN SA (CH) 2012-02-16 WO disclosed