Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489047 | 0.85 | L3MBTL1 (0.40) | — | |
| SCHEMBL6238476 | 0.79 | L3MBTL1 (0.41) | — | |
| SCHEMBL27511261 | 0.78 | POLB (0.46) | — | |
| SCHEMBL6762398 | 0.77 | SIRT2 (0.35) | KIF11 | |
| SCHEMBL7562211 | 0.77 | L3MBTL1 (0.40) | — | |
| SCHEMBL6238584 | 0.77 | ALDH1A1 (0.44) | KIF11 | |
| Hydrochloric Acid SCHEMBL6238911 | 0.76 | SIRT2 (0.35) | KIF11 | |
| SCHEMBL6235707 | 0.75 | IDO1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL6239812 | 0.74 | SIRT2 (0.34) | KIF11 | |
| SCHEMBL6235712 | 0.74 | CHRM2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392653-B1 | A SHORT SYNTHESIS OF PYRIDINE-BASED PHARMACEUTICAL INTERMEDIATES WITH SULFUR-CONTAINING GROUPS AT THE 2- AND 3-POSITIONS | UNIV NORTH CAROLINA STATE (US) | 2007-08-15 | — | — | EP | disclosed |
| EP-1222194-B1 | 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIC ACID ANTIBIOTICS AND PRODRUGS THEREOF | TRINE PHARMACEUTICALS INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6723716-B1 | BACTERICIDE FOR STAPHYLOCOCCUS | ESSENTIAL THERAPEUTICS, INC. | 2004-04-20 | — | — | US | disclosed |
| EP-1222194-A1 | 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIC ACID ANTIBIOTICS AND PRODRUGS THEREOF | Essential Therapeutics, Inc. (US) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001021623-A1 | 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIC ACID ANTIBIOTICS AND PRODRUGS THEREOF | ESSENTIAL THERAPEUTICS, INC. (US) | 2001-03-29 | — | — | WO | disclosed |