SCHEMBL62340

SCHEMBL62340

CCCCCNS(N)(=O)=O

nearest known ligand 0.86

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.86
CA1 P00915 5/20 0.86
PPARA Q07869 4/20 0.74
CA12 O43570 2/20 0.54
CA7 P43166 2/20 0.54
CA14 Q9ULX7 2/20 0.54
EPHX1 P07099 1/20 0.52
RELA Q04206 4/20 0.46
CA9 Q16790 1/20 0.44
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3124345 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL1228645 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL3792229 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL291897 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL80252 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL4622863 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL3794668 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL3312980 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL1668208 0.98 CA2 (0.82) CA2CA1PPARACA12CA7
SCHEMBL3787723 0.98 CA2 (0.82) CA2CA1PPARACA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1095 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149345-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO claimed
WO-2024151890-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-07-18 WO claimed
EP-4366777-A2 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-15 EP claimed
WO-2023280227-A2 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2023-01-12 WO claimed
CN-113444107-B Synthetic method and anticancer activity of succinimide spiro-fused sultams compound 河南师范大学 2022-05-24 CN claimed
CN-113444107-A Synthetic method and anticancer activity of succinimide spiro-fused sultams 河南师范大学 2021-09-28 CN claimed
WO-2021021904-A1 PHARMACOLOGICAL INHIBITORS OF THE ENL YEATS DOMAIN THE SCRIPPS RESEARCH INSTITUTE (US) 2021-02-04 WO claimed
CN-110218172-A A method of N- aryl sulfonic acid amides are prepared by indoline and aryl sulfonic acid amides 常州大学 2019-09-10 CN claimed
EP-2528922-B1 POLYHETEROCYCLIC COMPOUNDS AS HCV INHIBITORS AB PHARMA LTD (CN) 2017-08-02 EP claimed
EP-2751119-B1 FUSED BICYCLIC DIAMINE DERIVATIVES AS HIV ATTACHMENT INHIBITORS VIIV HEALTHCARE UK NO 5 LTD (GB) 2016-11-23 EP claimed
WO-1998008840-A1 INTEGRIN ANTAGONISTS MERCK & CO., INC. (US) 1998-03-05 WO claimed
WO-1997026250-A1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1997-07-24 WO claimed
WO-1997014417-A1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1997-04-24 WO claimed
EP-0426243-B1 Polyamide moulding compositions T & N TECHNOLOGY LTD (GB) 1996-03-20 EP claimed
CN-1111453-A Aryl sulfonamide derivatives and pharmaceutical compositions containing the same NIPPON KOKAN KK (JP) 1995-11-08 CN claimed
EP-0417721-B1 Novel peptidase and isomerase inhibitors MERRELL DOW PHARMA (US) 1995-09-06 EP claimed
US-5426022-A Silver halide emulsion layer, a color copler and a ultraviolet radiation stabilizer; used for colorphotography AGFA-GEVAERT AG (DE) 1995-06-20 US claimed
EP-0397427-B1 Fluoro-amide derivatives having human leucocyte elastase inhibiting activity ZENECA INC (US) 1994-05-04 EP claimed
US-5306609-A With nondiffusive coupler and acyl acetamide coupler of specified formulae; high color density, color image fastness FUJI PHOTO FILM CO., LTD. (JP) 1994-04-26 US claimed
WO-1992007836-A1 NOVEL SULFAMIDE DERIVATIVES, A METHOD FOR OBTAINING THEM AND THEIR USE AS A DRUG SHIMI IBRAHIM RAOUF (FR) 1992-05-14 WO claimed