SCHEMBL1228645

SCHEMBL1228645

CCCCCCCCCCCCCCCCCCNS(N)(=O)=O

nearest known ligand 0.82

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.82
CA1 P00915 6/20 0.82
PPARA Q07869 4/20 0.78
EPHX1 P07099 1/20 0.55
CA12 O43570 2/20 0.52
CA7 P43166 2/20 0.52
CA14 Q9ULX7 2/20 0.52
RELA Q04206 4/20 0.49
CA9 Q16790 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3108251 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
SCHEMBL80252 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
SCHEMBL1668208 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
SCHEMBL3787723 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
SCHEMBL3794668 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
SCHEMBL291897 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
SCHEMBL4622863 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
SCHEMBL3792229 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
SCHEMBL3124345 1.00 CA2 (0.82) CA2CA1PPARAEPHX1CA12
Fluoride SCHEMBL28507310 0.98 CA2 (0.78) CA2CA1PPARAEPHX1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459227-B1 Prodrugs containing an aromatic amine connected by an amide bond to a carrier ASCENDIS PHARMA AS (DK) 2021-03-17 EP claimed
EP-1984326-B1 ACYCLIC SULFAMIDE DERIVATIVES FUND IMABIS INST MEDITTERANEO PARA EL AVAN E DE LA BIOTECNOLOGIA Y LA INVESTIG SANITARIA (ES) 2017-05-03 EP claimed
US-9173953-B2 Prodrugs containing an aromatic amine connected by an amido bond to a linker ASCENDIS PHARMA AS (DK) 2015-11-03 US claimed
US-20120156260-A1 Prodrugs Containing an Aromatic Amine Connected By an Amido Bond to a Linker ASCENDIS PHARMA A/S (DK) 2012-06-21 US claimed
EP-2459227-A1 PRODRUGS CONTAINING AN AROMATIC AMINE CONNECTED BY AN AMIDO BOND TO A LINKER Ascendis Pharma A/S (DK) 2012-06-06 EP claimed
US-8188312-B2 Acyclic sulfamide derivatives FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) 2012-05-29 US claimed
WO-2011012722-A1 PRODRUGS CONTAINING AN AROMATIC AMINE CONNECTED BY AN AMIDO BOND TO A LINKER ASCENDIS PHARMA AS (DK) 2011-02-03 WO claimed
US-20100179224-A2 Acyclic Sulfamide Derivatives FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) 2010-07-15 US claimed
US-20100048712-A2 Acyclic Sulfamide Derivatives FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) 2010-02-25 US claimed
US-20090221710-A1 Acyclic Sulfamide Derivatives FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) 2009-09-03 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1984326-A1 ACYCLIC SULFAMIDE DERIVATIVES Fundacion Imabis. Inst. Meditteraneo para el Avan e de la Biotecnologia y la Investigacion Sanitaria (ES) 2008-10-29 EP claimed
WO-2007085469-A1 ACYCLIC SULFAMIDE DERIVATIVES FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) 2007-08-02 WO claimed
WO-2025129358-A1 STABLE FILM FORMULATIONS FOR HIGH LOADING OF LOW MELTING POINT ACTIVES INTELGENX CORP. (CA) 2025-06-26 WO disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed
US-5126234-A Pyrazolone-based magenta coupler; low fog, high color density FUJI PHOTO FILM CO., LTD. (JP) 1992-06-30 US disclosed
US-4078930-A ELECTROSTATOGRAPHIC XEROX CORPORATION (US) 1978-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120156260-A1 Prodrugs Containing an Aromatic Amine Connected By an Amido Bond to a Linker DAO, DNPEP, DDC CA2 857/4885CA1 1173/4885PPARA 2083/4885
US-20100179224-A2 Acyclic Sulfamide Derivatives SULT2A1, STS, SUCNR1 CA2 1092/4885CA1 1840/4885PPARA 346/4885
US-20090221710-A1 Acyclic Sulfamide Derivatives STS, LIPE, FABP4 CA2 2198/4885CA1 3726/4885PPARA 30/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 CA2 3860/4885CA1 2620/4885PPARA 4186/4885
US-20100048712-A2 Acyclic Sulfamide Derivatives SULT2A1, STS, SUCNR1 CA2 1092/4885CA1 1840/4885PPARA 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.